In addition to the active pharmaceutical ingredient, drug formulations contain excipients such as stabilizers, colourants and antioxidants, which are designated as ‘inactive’. However, writing in Science, researchers from academia and industry now report that many commonly used excipients are active at physiologically relevant targets, suggesting more attention should be paid to these often-overlooked drug components. The FDA’s Inactive Ingredients Database (IID) lists more than 3,000 excipients, which are considered inactive […]